A sugar-packed diet can take its toll on your waistline, but now experts also believe it can make your skin dull and wrinkled too. To blame is a natural process known as glycation, in which the sugar in your bloodstream attaches to proteins to form harmful new molecules called advanced glycation end products (AGEs, for short). The more sugar you eat, the more AGEs you develop; these damage surrounding proteins like collagen and elastin, which keep skin firm and elastic. Once damaged, springy and resilient collagen and elastin become dry and brittle, leading to wrinkles and sagging. These aging effects start at about age 35 and increase rapidly after that,

You don’t feel good when you’re stressed-out — be it from work projects piling up, a miserable commute, issues with the kids, etc. — and there’s good biological proof why you shouldn’t. Stress increases the concentration of the hormones cortisol and norepinephrine in the bloodstream, kicking up blood pressure and suppressing immunity. Over time, stress that doesn’t go away can delay healing, harden your arteries, and possibly shrink areas of your brain involved in learning, memory, and mood—talk about feeling older!

Exercise is one of the best turn-back-the-clock agents around, but too many of us don’t reap its full benefits because we only associate physical activity with weight loss. If you tend to hit the gym in 2-week stints to shed a few pounds, but then take a few months off from physical activity, you’re missing out on some major health perks. Research shows that vigorous exercisers have longer telomeres — cellular biomarkers that shorten as we age — compared with healthy adults who rarely work out. Being active consistently can help fight brain fog, reduce inflammation, and prevent type 2 diabetes and other chronic conditions that crop up over time.

Your friends were probably the meat and potatoes of your social calendar back in your 20s; now you spend most of your spare time shuttling your tweens around to their various get-togethers. But here’s why making time to cultivate your friendships is so key: One study found that satisfying friendships predict longevity better than even close family ties, and they can protect against obesity, depression, and heart disease, among other health problems. No wonder you always feel reenergized after a marathon catch-up call with your best college friend or a girls’ night out with your high school crew.

You’ve likely heard that antioxidant-packed fruits and veggies can help you stay young. These powerful compounds fight free radicals that would otherwise wreak havoc on your body and skin, damaging cells that can lead to cancer and make you look older. But here’s the rub: Antioxidants remain active for only a few hours and need to be continually replenished, so don't think you're set for the week after eating a big salad for lunch on Monday.

Cutting out artery-clogging saturated and trans fats is a heart-healthy move, but when it comes to your health and vitality, equally slashing unsaturated fats, like those found in fish, nuts, and olive oil, is like throwing the proverbial baby out with the bathwater. One kind, omega-3 fatty acids, is the ultimate anti-aging fat, essential for protecting your brain, heart, bones, joints, skin, and more. Another kind, monounsaturated, can lower bad LDL cholesterol, raise cardio-protective HDL cholesterol, and decrease your risk of atherosclerosis.